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A recent case study describes an example of gastrointestinal treatment inducing full remission of rosacea symptoms. The authors of the paper hypothesise that GI tract bacteria may in some people cause a chronic inflammatory reaction affecting the blood vessels.

Rosacea is a chronic disorder characterized by hypersensitivity of the facial vasculature, presenting with intense flushing eventually leading to chronic erythema and telangiectasia. Although the precise aetiology of rosacea is not known, numerous associations with inflammatory gastrointestinal tract disorders have been reported. Furthermore, substance P-immunoreactive neurones occur in considerably greater numbers in tissue surrounding affected blood vessels suggesting involvement of neurogenic inflammation and moreover plasma kallikrein-kinin activation is consistently found in patients. In this report, a patient without digestive tract disease is described, who experienced complete remission of rosacea symptoms following ingestion of a material intended to sweep through the digestive tract and reduce transit time below 30 h. It is possible that intestinal bacteria are capable of plasma kallikrein-kinin activation and that flushing symptoms and the development of other characteristic features of rosacea result from frequent episodes of neurogenic inflammation caused by bradykinin-induced hypersensitization of facial afferent neurones.

The case study doesn’t mention seabuckthorn, but it provides much food for thought regarding the relationship between seabuckthorn, gastrointestinal disorders, inflammatory diseases, and rosacea.

Seabuckthorn has long been known for healing gastrointestinal disorders, including bacterially induced ulcers. It has also been known to heal rosacea, in particular with its anti-inflammatory actions. However, what if part of seabuckthorn’s strength in treating rosacea is due to its salutary affect on the gastrointestinal system?

This article also bolsters several of the cornerstones of our rosacea treatment philosophy, including our belief in the ‘inside out’ treatment of rosacea (treating the whole body, not only the skin), and our belief that rosacea is a symptom of an out-of-control inflammatory response.

The possible relevance of this hypothesis to other conditions featuring afferent hypersensitivity, such as fibromyalgia, is considered.

A recent NYTimes article (free registration required) looked at fibromyalgia in light of the recent approval of a non-narcotic pain management drug manufactured by Pfizer for the treatment of the disorder. The article takes a sceptical view, going so far as to quote at length medical professionals who dismiss fibromyalgia as some people’s inability to cope with the aches and pains of living.

Most people “manage to get through life with some vicissitudes, but we adapt,” said Dr. George Ehrlich, a rheumatologist and an adjunct professor at the University of Pennsylvania. “People with fibromyalgia do not adapt.”

But there is growing evidence that people with fibromyalgia improve significantly or completely when they take SBT Seabuckthorn.

We at Seabuckthorn International Inc. have long believed that part of SBT Seabuckthorn’s strength is its ability to counter the cumulative deleterious effects of the modern world on our bodies. A less-than-optimally-functioning gastrointestinal tract is a predictable symptom of such effects. If seabuckthorn heals fibromyalgia and rosacea, and seabuckthorn heals gastrointestinal disorders; and if gastrointestinal disorders cause chronic inflammation, which is culpable in rosacea and fibromyalgia, the cause and effect relationship seems self-evident.



Seabuckthorn and Inflammation – from Seabuckthorn.com (HTML version)Seabuckthorn and Inflammation – from Seabuckthorn.com (.PDF version)
SBT Seabuckthorn capsules – from Seabuckthorn.com
SBT Seabuckthorn tea – from Seabuckthorn.com
SBT Seabuckthorn Fibromyalgia Page – from Seabuckthorn.com

3 Responses to “Treatment of gastrointestinal inflammation induces rosacea remission: significant for seabuckthorn research? And what about fibromyalgia?”

  1. I have fibromyalgia since 1992 due to a serious car accident and have a great deal of pain about the shoulders, neck and lower back. Could you tell me more about your product. Is it a tea or capsules or a cream? Thank you for your time and attention. sincerely Patti

  2. Hi patti:
    Thanks for dropping by the blog! I’m very sorry about your problems with fibromyalgia. We offer a full line of skincare products and nutritional supplements containing seabuckthorn – the plant itself can be made into a variety of things, and so it is all the things you listed! You might try checking out our fibromyalgia package at the link above, or just drop by http://www.seabuckthorn.com.

  3. Interesting post. I have recently read a few articles suggesting that seabuckthorn may be an “adaptogen”. Wikipedia defines an adaptogen as:
    The term adaptogen is used by herbalists to refer to a natural herb product that is proposed to increase the body’s resistance to stress, trauma, anxiety and fatigue. In the past, they have been called rejuvenating herbs, qi tonics, rasayanas, or restoratives. All adaptogens contain antioxidants, but antioxidants are not necessarily adaptogens and that is not proposed to be their primary mode of action.[1]

    The concept of adaptogens dates back thousands of years to ancient India and China, but modern study did not begin until the late 1940s. In 1947, Nikolai Lazarev defined an adaptogen as an agent that allows the body to counter adverse physical, chemical, or biological stressors by raising nonspecific resistance toward such stress, thus allowing the organism to “adapt” to the stressful circumstances.[1]

    In 1968, Israel I. Brekhman , PhD, and I. V. Dardymov formally gave adaptogens a functional definition, as follows:

    An adaptogen is nontoxic to the recipient.
    An adaptogen produces a nonspecific response in the body—an increase in the power of resistance against multiple stressors including physical, chemical, or biological agents.
    An adaptogen has a normalizing influence on physiology, irrespective of the direction of change from physiological norms caused by the stressor.
    Under this definition, adaptogens would be nontoxic in normal doses, produce a general defensive response against stress, and have a normalizing influence on the body.[1]

    It is claimed that adaptogenic herbs are distinct from other substances in their ability to balance endocrine hormones and the immune system, and they help the body to maintain optimal homeostasis.[1] Adaptogens are proposed to have a normalizing effect on the body and to be capable of either toning down the activity of hyperfunctioning systems or strengthening the activity of hypofunctioning systems. However, they are also proposed to be functional at the level of allostasis, which is a more dynamic reaction to long term stress, lacking the fixed reference points of homeostasis.[2]

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